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Drugs for digestive disorders
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Antacids are drugs that neutralize excess acid to relieve indigestion or help peptic ulcers to heal.

Common drugs

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  • Activated dimeticone
  • Alginates
  • Aluminium hydroxide
  • Calcium carbonate
  • Magnesium hydroxide
  • Sodium bicarbonate

Antacids are used to relieve upper abdominal discomfort caused by irritation of the stomach or duodenum (see Indigestion). Antacids can also relieve the discomfort caused by gastro-oesophageal reflux disease, in which stomach acid is regurgitated into the oesophagus. They may help to ease symptoms due to peptic ulcers.

Antacid preparations may contain aluminium and/or magnesium salts, both of which neutralize stomach acid (see How antacids work). Some contain additional ingredients such as activated dimeticone, which disperses bubbles of gas to reduce bloating, or alginates, which provide a protective coating for the oesophagus if regurgitation of the stomach contents occurs. If indigestion persists for more than a week, see your doctor.

What are the side effects of antacids?

Most antacid preparations have very few side effects. However, antacids containing aluminium can occasionally cause constipation, while those that contain magnesium may cause diarrhoea. The antacid sodium bicarbonate may produce excess gas in the stomach, which can cause abdominal bloating. Sodium bicarbonate may cause fluid retention in people who have kidney disease or chronic heart failure and should therefore be avoided by anyone with these conditions.

Consult your doctor before using antacids if you are already taking other medication; antacids can interfere with the body's absorption of certain drugs.

Posted 09.09.2010


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